Therapy/Class:
Therapy: Nasal decongestant
Class: Direct Alpha-Adrenergic Receptor Agonist
Mechanism of Action:
It is a sympathomimetic agent acting on alpha‐adrenergic receptors in the nasal mucosa. it constricts the nasal blood vessels, thereby decongesting the mucosa of the nose. It also reduces associated symptoms of mucus hypersecretion and facilitates drainage of blocked secretions. This decongests nasal passages and enables patients suffering from blocked nose to breathe more easily through the nose.
Indications:
- For Temporary relief of blocked nose caused by colds, hay fever or other allergic rhinitis, sinusitis etc.
Dosage & Administration:
- Dosage for Children (6-11 years)
- Administer 2 sprays or 2-3 drops into each nostril up to 3 times a day.
- Do not exceed 3 doses within 24 hours.
- Not suitable for children under 6 years of age.
HOW SUPPLIED: NAZOPUMP JR NASAL SPRAY is available as Nasal Spray in 10ml pack.
References:
- Graf C, Bernkop-Schnürch A, Egyed A, Koller C, Prieschl-Grassauer E, Morokutti-Kurz M. Development of a nasal spray containing xylometazoline hydrochloride and iota-carrageenan for the symptomatic relief of nasal congestion caused by rhinitis and sinusitis. Int J Gen Med. 2018 Jul 4;11:275-283.
- Joganathan V, Beigi B. Safety of the use of xylometazoline nasal spray in young children undergoing lacrimal surgery: an observational study. European Journal of Ophthalmology. 2018;28(3):279-281.
- Hamilton, L. H. (1981). Effect of xylometazoline nasal spray on nasal conductance in subjects with coryza. The Journal of Otolaryngology, 10(2), 109-116.
