Phentastik Syrup

Composition: Each 5 mL of Phentastik contains 5 mg of Promethazine pack in a 100ml syrup.

Formulation: Oral syrup

Flavour: Pineapple Flavour

Category:

Therapy/Class: Antihistamine/First-generation H1 receptor antagonist

Mechanism of Action:

Antidopaminergic Effect: Promethazine acts as a direct antagonist at the mesolimbic dopamine receptors in the brain, which helps in reducing nausea and vomiting.

Antihistamine Effect: Promethazine exhibits its antihistamine properties as an H₁-receptor blocker, reducing allergic responses and providing relief from symptoms like itching and rashes.

Indications:

  • Treatment of Perennial & Seasonal Allergic Rhinitis
  • Allergic Conjunctivitis
  • Motion Sickness
  • Nausea & Vomiting Post-Surgery

Dosage & Administration:

More than 2 Years Age: 0.25-1mg/kg every 4-6 Hrs as & when required. Maximum Dose:25mg/day

How Supplied:

Phentastik syrup is supplied in a 100ml bottle pack.

References:

  • Aust Prescr. 2020 Apr 1;43(2):49–56.
  • Treasure Island (FL): StatPearls Publishing; 2025 Jan
error: Content is protected !!