Ximclor Suspension

XIMCLOR SUSPENSION: Each 5ml suspension contains Chloramphenicol 125mg in 60ml Pack.

Formulation: Suspension

Flavour: Mix Fruit Flavour


Therapy / Class: Antibacterial / Amphenicol-class Antibacterial

Spectrum of Coverage:

  • Haemophilus Influenza
  • Neisseria meningitidis
  • Streptococcus pneumoniae
  • Salmonella enterica serotype Typhi
  • Rickettsia
  • Lymphogranuloma-psittacosis group
  • Escherichia coli
  • Staphylococcus aureus

Mechanism of Action:

Works by inhibiting protein synthesis by binding to the 50S ribosomal subunit & directly preventing the formation of bacterial protein. On a molecular level, chloramphenicol inhibits the attachment of transfer RNA to the A site on the 50S ribosome.


  • Rickettsial Diseases
  • Meningitis
  • Typhoid Fever
  • Cholera

Dosage & Administration:

  • Moderate Infections: 50mg/kg/day, given in 4 divided doses at 6 hours interval.
  • Severe Infections (Meningitis & Bacteraemia): 100mg/kg/day, given in 4 divided doses at 6 hours interval with an attempt for dose reductions back to 50mg/kg/day made as soon as possible. Also, dose reductions to 25mg/kg/day may be necessary for neonates, and patients who have impaired liver or renal function.


XIMCLOR is available as oral suspension in 60ml Pack.


  1. Cochrane Database Syst Rev. 2017 Jun 14;6(6)
  2. Infect Drug Resist. 2019; 12:3217-3225
  3. J Chemother. 2016 Jun;28(3):143-50


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