Disopod Tablets

Composition:

DISOPOD 50 DT: Each Tablet contains Cefpodoxime 50mg in Dispersible tablet

DISOPOD 100 DT: Each Tablet contains Cefpodoxime 100mg in Dispersible tablet

Formulation: Dispersible Tablets

Flavour:

Disopod 50 DT – Orange Flavour

Disopod 100 DT – Orange and Peppermint Flavour

Category:

Therapy / Class: Antibacterial/Third-Generation Cephalosporin Antibiotic

Spectrum of Coverage

Gram-positive bacteria:

  • Staphylococcus aureus (methicillin-susceptible strains, including those producing penicillinases)
  • Staphylococcus saprophyticus
  • Streptococcus pneumoniae (excluding penicillin-resistant isolates)
  • Streptococcus pyogenes

Gram-negative bacteria:

  • Escherichia coli
  • Klebsiella pneumoniae
  • Proteus mirabilis
  • Haemophilus influenzae (including beta-lactamase producing isolates)
  • Moraxella catarrhalis
  • Neisseria gonorrhoeae (including penicillinase-producing isolates)

Mechanism of Action:

Shows bactericidal action by inhibition of bacterial cell wall synthesis. Active against some beta-lactamases, both penicillinasesand cephalosporinases, of Gram-negative and Gram-positive bacteria.

Indications:

  1. Acute otitis media
  2. Pharyngitis and/or tonsillitis
  3. Community-acquired pneumonia
  4. Acute bacterial exacerbation of chronic bronchitis
  5. Uncomplicated skin and skin structure infections
  6. Acute maxillary sinusitis
  7. Uncomplicated urinary tract infections

Dosage & Administration:

Infants and Pediatric Patients (age 2 months through 12 years)

Type of Infection   

Total Daily Dose

Dose Frequency

Duration

Acute otitis media  

10 mg/kg/day
(Max 400 mg/day)  

5 mg/kg Q 12 h
(Max 200 mg/dose)

5 days

Pharyngitis and/or tonsillitis

10 mg/kg/day
(Max 200 mg/day)

5 mg/kg/dose Q 12 h
(Max 100 mg/dose)

5 to 10 days

Acute maxillary sinusitis

10 mg/kg/day
(Max 400 mg/day) 

5 mg/kg Q 12 hours
(Max 200 mg/dose)

10 days

 

HOW SUPPLIED:

DISOPOD 50 DT available as Dispersible Tablet in 10 x 10 Aluminum Strip

DISOPOD 100 DT available as Dispersible Tablet in 10 x 10 Aluminum Strip

References:

  1. J Clin DiagnRes . 2017 Jun;11(6):FC01-FC04. 
  2. Journal of Antimicrobial Chemotherapy (2002) 50, Topic T1, 23–27
  3. Drugs Context. 2020; 9: 2020-9-3.

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