Therapy/Class: Antihistamine / Second-Generation H1 Receptor Antagonist
Mechanism of Action:
- Cetirizine is a selective H1 receptor antagonist that blocks histamine’s action
Indications:
- Allergic rhinitis (seasonal and perennial).
- Chronic urticaria (hives).
- Allergic conjunctivitis.
- Skin allergic reactions (e.g., itching, redness).
Dosage & Administration:
For Children 12 Years and Older:
- 5–10 mg (5–10 mL) once daily, depending on symptom severity.
For Children Aged 6 to 11 Years:
- 5–10 mg (5–10 mL) once daily, depending on symptom severity.
For Children Aged 2 to 5 Years:
- Initial dose: 2.5 mg (2.5 mL) once daily.
- May be increased to a maximum of 5 mg (5 mL) per day, either as 5 mL once daily or 2.5 mL every 12 hours.
For Children Aged 6 Months to Under 2 Years:
- Initial dose: 2.5 mg (2.5 mL) once daily.
- For children 12 to 23 months, the dose can be increased to a maximum of 5 mg per day, given as 2.5 mL every 12 hours.
How Supplied:
Heyciri is supplied in 60 mL syrup bottles.
References:
- Cetirizine Hydrochloride Drug Information
- FDA Label for Cetirizine Hydrochloride https://www.accessdata.fda.gov/drugsatfda_docs/label/2002/19835s15,%2020346s8lbl.pdf