Gripedia XL Suspension


GRIPEDIA DROPS: Each 1ml contains Dicyclomine 10 mg & Activated Dimethicone 40 mg as Drops in 10ml Pack.

GRIPEDIA SYRUP: Each 5ml contains Dicyclomine 10 mg, Activated Dimethicone 40 & Domperidone 5mg as Syrup in 30ml Pack.

GRIPEDIA XL SUSPENSION: Each 5ml contains Dicyclomine 10 mg & Activated Dimethicone 40 as Suspension in 60ml Pack.

Formulation: Drops & Suspension

Flavour: Mango

Categories: , ,


Dicyclomine: Antispasmodic,

Activated Dimethicone: Antiflatulent,

Domperidone: Anti-Emetic


Dicyclomine: Muscarinic Receptor Antagonist

Activated Dimethicone: Oil of Silicone (Polydimethylsiloxane)

Domperidone: Dopamine Receptor Antagonist

Mechanism of Action:

Dicyclomine: It is a muscarinic M1, M3, and M2 receptor antagonist as well as a non-competitive inhibitor of histamine and bradykinin used to treat spasms of the intestines seen in functional bowel disorder and irritable bowel syndrome

Activated Dimethicone: It act by decreasing the surface tension of gas bubbles in the GI tract. This action results in coalescence and dispersion of the gas bubbles allowing their removal from the GI tract as flatulence or belching. It causes the gas bubbles to accumulate and therefore pass more easily either through the upper GI or lower GI opening.

Domperidone: Its Antiemetic properties of domperidone are related to its dopamine receptor blocking activity at both the chemoreceptor trigger zone and at the gastric level. It has strong affinities for the D2 and D3 dopamine receptors, which are found in the chemoreceptor trigger zone, located just outside the blood brain barrier, which – among others – regulates nausea and vomiting


  • Functional Bowel Disorders, Particularly Irritable Bowel Syndrome (IBS)
  • Gastric Distention
  • Functional Digestive Disorders
  • Stomach Pain
  • Spasms associated with Gastritis (Stomach Inflammation)
  • Spasms associated with Gastrointestinal Infection

Dosage & Administration:

Infants more than 6 Months
In Spasm: GRIPEDIA DROPS: 1ml to 2ml-3 to 4 times a Day
In Spasm: GRIPEDIA XL SUSPENSION 5ml 3 to 4 times a Day
In Spasm associated with Vomiting: GRIPEDIA SUSPENSION 5ml 3 to 4 times a Day
Administer the medication half to one hour before meals.


GRIPEDIA DROPS is available as Drops in 10ml Pack.
GRIPEDIA SUSPENSION is available as Suspension in 30ml Pack.
GRIPEDIA XL SUSPENSION is available as Suspension 60ml Pack.


  1. Weissbluth M, Christoffel KK, Davis AT. Treatment of infantile colic with dicyclomine hydrochloride. J Pediatr. 1984 Jun;104(6):951-5. doi: 10.1016/s0022-3476(84)80506-5. PMID: 6374085.
  2. Ihde ES, Boscamp JR, Loh JM, Rosen L. Safety and efficacy of a 100% dimethicone pediculocide in school-age children. BMC Pediatr. 2015 Jun 20;15:70. doi: 10.1186/s12887-015-0381-0. Erratum in: BMC Pediatr. 2016;16:12. PMID: 26092045; PMCID: PMC4475297.
  3. Bines JE, Quinlan JE, Treves S, Kleinman RE, Winter HS. Efficacy of domperidone in infants and children with gastroesophageal reflux. J Pediatr Gastroenterol Nutr. 1992 May;14(4):400-5. doi: 10.1097/00005176-199205000-00005. PMID: 1517943.


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