Parajely Drops

Composition:

PARAJELY 100 DROPS: Each 1ml contains Paracetamol 100mg in Drops in 15ml Pack.
PARAJELY 150 DROPS: Each 1ml contains Paracetamol 150mg in Drops in 30ml Pack.

Formulation: Drops

Flavour: Mango Flavour

Category:

Therapy / Class: Analgesics & Antipyretic / Para Aminophenol Derivatives

Mechanism of Action:

Analgesic Mechanism: It produces analgesic action by inhibiting the COX pathway in the central nervous system but not in peripheral tissues. It acts within the CNS to increase the pain threshold by inhibiting central cyclo-oxygenase (Both COX-1 & COX-2).

Anti-Pyretic Mechanism: It also produces antipyretic effect by inhibiting PG synthesis in the central nervous system & blocking the actions of endogenous pyrogens at the hypothalamic thermo-regulatory centers.

Indications:

  1. Treatment Of Fever
  2. Treatment of Mild Pain or for the temporary relief of
    • Headache
    • Myalgia
    • Back Pain
    • Musculoskeletal Pain
    • Dental Pain (E.G., Toothache)
    • Dysmenorrhea, Arthralgia
    • Minor Aches & Pains Associated with Common Cold or Flu
  3. Moderate Pain to Severe Pain with Adjunctive Opioid Analgesics
  4. Acute Treatment of Migraine

Dosage & Administration:

For Suspension/Dispersible Tablets
Age GroupDose given every 4 hoursDose given every 6 hoursMaximum single doseMaximum total daily dose of Paracetamol
Children 2 to 12 years of age12.5mg/kg15mg/kg15mg/kg (up to 750mg)75mg/kg in 24 hours (up to 3,750mg)
For Drops
Average Weight (Kg)Dose* (ml)
3.8-5.50.5-0.8
5.5-8.30.8-1.2
8.3-101.2-1.5
*Calculated based on 15mg/kg body weight

HOW SUPPLIED:
PARAJELY-100 is available as Drops in 15ml Pack.
PARAJELY-150 is available as Drops in 30ml Pack.

References:

  • Cochrane Database Syst Rev. 2002;2002(2)
  • Scand J Prim Health Care. 2010; 28(2): 115–120.
  • Eur J Pediatr. 2022 May;181(5):1835-1857.
  • Inflammopharmacology. 2017; 25(1): 1–9.
  • Pain Ther. 2015 Dec;4(2):149-68.
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