Each 5ml contains Clarithromycin 125 mg in 30ml pack 

Formulation: Dry Syrup

Flavour: Banana Flavour


Therapy / Class: Antibacterial / Macrolide Class

Spectrum of Coverage:

Aerobic Gram-positive microorganisms

Atypical / Other microorganisms

Streptococcus pyogenes

Chlamydophila pneumoniae

Aerobic Gram-negative microorganisms

Legionella pneumophila

Haemophilus influenzae

Mycobacterium avium

Moraxella catarrhalis

Mycobacterium chelonae

Helicobacter pylori

Mycobacterium intrazellulare


Mycoplasma pneumoniae

Mechanism of Action:

Works by stopping the growth of bacteria. It binds to the 50s ribosomal sub-unit of susceptible bacteria. 


  • Infections of the upper respiratory tract such as tonsillitis/pharyngitis, as an alternative when betalactam antibiotics are not appropriate. 
  • Acute otitis media in children.
  • Infections of the lower respiratory tract such as community acquired pneumonia.
  • Sinusitis and acute exacerbation of chronic bronchitis in adolescents over 12 years of age
  • Skin infections and soft tissue infections of mild to moderate severity.

Dosage & Administration:

Children 6 months to 12 years of age

The recommended dose is 7.5 mg/kg twice a day.




8 – 11 kg

1 – 2 years

2.5ml twice daily

12 – 19 kg

2 – 4 years

5ml twice daily

20 – 29 kg

4 – 8 years

7.5ml twice daily

30 – 40 kg

8 – 12 years

10ml twice daily

Children weighing less than 8 kg should be treated based on their bodyweight.


CALOF-DS is Dry Syrup available as 30ml pack with sterile water 


  1. Gutiérrez-Castrellón P, et al. Meta-analysis of clarithromycin in children with respiratory infections. n ClRev Invest Clin 2012; 64 (2): 126-135
  2. Pediatr Infect Dis J. 1993 Dec;12(12 Suppl 3):S122-7
  3. Indian J Otolaryngol Head Neck Surg. 2018 Mar; 70(1): 87–91.


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