Bendigo Suspension

Composition:

Each 5ml contains Albendazole 200mg in suspension in 10ml Pack.

Formulation: Suspension

Flavour: Orange Flavour

Category:

Therapy / Class: Anti-Helmintic / Anti Parasitic Agent/ Benzimidazole Class

Spectrum of Coverage: Active against the larval forms of organism:

  • Echinococcus granulosus
  • Taenia solium

Mechanism of Action:

It works by inhibiting protein synthesis by binding to the 50S ribosomal subunit & directly preventing the formation of bacterial protein. On a molecular level, chloramphenicol inhibits the attachment of transfer RNA to the A site on the 50S ribosome.

Indications:

  • Hydatid Cyst Disease
  • Neurocysticercosis
  • Cysticercosis
  • Ascariasis (Roundworm Infection)
  • Capillariasis
  • Secondary Treatment of Cutaneous Larva Migrans
  • Microsporidiosis & Secondary Microsporidiosis Prophylaxis
  • Strongyloidiasis
  • Trichinosis
  • Enterobiasis (Pinworm Infection)
  • Hookworm Infection
  • Trichuriasis (Whipworm Infection)
  • Giardiasis

Dosage & Administration:

  • Hydatid Cyst Disease: 15mg/kg/day orally given in 2 divided doses (Max: 800mg/day) for 28 days
    followed by a 14-day drug-free period. Repeat for 2 more cycles.
  • Neurocysticercosis: 15mg/kg/day (Max: 1,200mg/day) orally in 2 divided doses for 10 to 14 days
    combined with praziquantel and corticosteroids.
  • Cysticercosis: 15mg/kg/day orally given in 2 divided doses (Max: 800mg/day) for 8 to 30 days.
  • Ascariasis (Roundworm Infection): 400mg orally as a single dose.
  • Capillariasis (Children 2 years and older): 200mg orally twice daily for 10 days.
  • Cutaneous Larva Migrans: 5mg/kg/day orally for 3 days.
  • Microsporidiosis: 7.5mg/kg/dose (Max: 400mg/dose) orally twice daily for 7 days.
  • Strongyloidiasis: 400mg orally twice daily for 7 days.
  • Trichinosis: 400 mg orally twice daily for 8 to 14 days.
  • Enterobiasis (Pinworm Infection): Age 2 to 17 years: 400mg orally as a single dose; repeat dose in
    2 weeks & Age 1 year: 200 to 400mg orally as a single dose; repeat dose in 2 weeks.
  • Hookworm Infection: 400mg orally as a single dose.
  • Giardiasis: 10 mg/kg/dose (Max: 400mg/dose) orally once daily for 5 days.

HOW SUPPLIED: BENDIGO is available as oral suspension in 10ml Pack.

References:

  1. Indian Pediatr. 2022 Dec 15;59(12):916-919. Epub 2022 Oct 29.
  2. DtschArztebl Int. 2019 Mar; 116(13): 213–219.
  3. Am J Trop Med Hyg. 2017 Feb 8; 96(2): 347–354.
  4. Trans R Soc Trop Med Hyg. 1994 Jan-Feb;88(1):110-2.

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